Parkinson's Disease is a neurodegenerative condition
caused by progressive loss of dopamine producing nerve cells in
the brain. The loss of dopamine causes critical nerve cells to
fire out of control, resulting in dramatic affects on motor function
including tremor, rigidity, and difficulty initiating movement.
Existing drugs help patients manage many of the symptoms for some
time but they do not stop disease progression.
in cognition occur with normal aging, but more drastic changes
are hallmarks of Alzheimer’s disease which
causes a catastrophic degradation of the quality of life for an
individual and his or her family. There is no cure and current
treatments only modestly delay the disease’s progression.
Schizophrenia has positive and negative symptoms.
Positive symptoms include hallucinations, delusions, disorganized
thinking and behavioral
problems. Negative symptoms include withdrawal, apathy, and difficulty
holding a job. Schizophrenics may also suffer from memory and
cognitive disturbances. Current medications are ineffective against
symptoms and cognitive deficits.